Universidade de Pernambuco-UPE

The Universidade de Pernambuco (UPE)

UPE is the public university of the State of Pernambuco, linked to the Secretariat of Science and Technology of the State. UPE´s mission is to contribute to the sustainable development of Pernambuco through teaching, research and university extension activities. UPE is a multicampi university combining teaching and research units distributed in all regions of the State and three university hospitals.

The UPE offers 13 Master courses and four PhD courses. The Programa de Pós-Graduação em Ciências da Saúde (Health Sciences Postgraduate Program) – Master degree and PhD degree – and the “Mestrado em Biologia Celular e Molecular Aplicada” (Master degree in Applied Cellular and Molecular Biology) develop collaborative work with other Brazilian and foreign institutions and have intersecting areas of interest with the LSHTM.

The Programa de Pós-Graduação em Ciências da Saúde (Health Sciences Postgraduate Program) aim to train researchers with autonomy and ability to plan, develop and implement research, education and extension in the area of Health Science, in an interdisciplinary way with multifaceted vision. It is composed of 20 professors/researchers including 13 researchers from clinical and epidemiological area, six from the basic area and one biostatistician. The group has experience with multidisciplinary working in research projects involving teams of teachers from different areas of knowledge.

The Master course in Applied Cellular and Molecular Biology has focused on the training of human resources to act as researchers/scientists and technological education institutions. This area covers the studies of macromolecules at the ultrastructural level, functional processes and applications of cellular markers for different purposes. There are three lines of research: 1) Structural and functional analysis of cells and cytological markers; 1) Study of biomolecular processes and application of diagnostic molecular markers; 3) Development of products involving living organisms and part of them.

The two university hospitals, HUOC and PROCAPE, are regional reference in infectious diseases, cardiology and oncology with infrastructure that ensures qualified medical assistance. The Multiuser Laboratory and other research laboratories: Molecular Biology of Viruses; Immunobiology and Parasitology; the Center for Pediatric Onco-hematology; the Center of Experimental Surgery support basic research in the area.

Listed below are some areas of study for which there is a potential for collaborative work with LSHTM:

A cohort of about 2300 patients with HIV/AIDS has been monitored since 2007 (Cohort AIDS-PE) in a collaborative study also involving the Universidade Federal de Pernambuco (UFPE) and the Oswaldo Cruz Foundation (FIOCRUZ-PE). Metabolic changes, cardiovascular complications and co-infection with tuberculosis are some of the aspects which are being investigated;

Cost-effectiveness of expanding rapid test for the diagnosis of HIV infection for the Basic Health Units and cost-effectiveness of first-line antiretroviral regimens offered by the National Health System for the treatment of HIV infection in collaboration with UFPE, FIOCRUZ-PE, Secretaria de Saúde de Pernambuco (Health Secretariat of Pernambuco) and LSHTM;

  • Clinical and epidemiological studies in HIV/AIDS and visceral leishmaniasis co-infection;
  • Validation of polymerase chain reaction and direct agglutination test in the diagnosis of visceral leishmaniasis;
  • Genetic polymorphism in degenerative diseases, in solid tumors and hematologic malignancies;
  • Physiopathologic mechanisms of infectious diseases and chronic diseases including studies of various genetic polymorphisms;
  • Gene polymorphism of interleukin 10 (IL-10), mannose binding lectin (MBL2) and myeloperoxidase (MPO) in chronic diseases



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